The MicroFLO™ reactor is a plate-type reactor incorporating the split and recombine strategy for effective mixing. Its high heat transfer area per unit volume ensures near isothermal conditions even for very fast, highly exothermic reactions like lithiations, Grignard synthesis, and nitrations. The MicroFLO™ reactor, in particular, has been designed to maximize process volume in a given footprint due to its unique “space-filling” configuration. The MicroFLO™ reactor is a superb mixing and heat dissipation device. The reactor can tolerate much higher pressures (of the order of 100 bar) than glass or ceramic micro-reactors.