Nanomake

  • Fully automated operation
  • Single Use and Multi use microfluidic chip
  • Wide range of flow rates on single platform
  • Configurable 3 precursor pumps
  • Built in washing program
  • Enables microfluidic chips different internal volumes on same platform
  • Easily replaceable 2 mL, 15 mL and 50 mL sample collection attachments

Application: NanoMake has a wide range of applications in:

  • Liposomes
  • MRNA lipid nanoparticles
  • Drug Loaded Nanoparticles
  • Metallic nanoparticle

Formulating nanomedicine is one of the major challenges towards translation. The in-vivo distribution, uptake, and clearance of NPs are influenced by their size, making it a vital parameter to regulate. The formulation of nanomedicine normally possesses batch-to-batch variability by conventional methods, restricts translation and results in procedures that are difficult to scale from the discovery stage of a study through animal testing, clinical testing, and eventually commercial manufacturing.

Microfluidic technologies have been employed to formulate nanomedicine with better controllable physical characteristics. We deploy our patented technology for formulating such anoparticles with desirable features to solve the present issues associated with it. The NanoMake technology is a simple to use microfluidic platform designed to enable rapid optimization and formulation of nanomedicine with optimal setup and training.

Technical Specification NanoMake
Flow rates 100 µL/min to 50 ml/min
Temperature Ambient – 80 °C (optional preheater)
No. of pumps (precursor) 3
Syringe sizes 500 µl, 1, 2.5, 5, 10, 25 mL
Microreactor Single Use and Multi use microreactors with different internal volumes
Nanomaterial synthesis Lipid, polymer, metal

 

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